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Principles of Inheritance and Variation

The family pedigree of Queen Victoria shows a number of descendants for which of genetical disease
A. Haemophilia
B. Thalassemia
C. Sicklecell anemia
D. Phenyl Ketonusia

A. Haemophilia

It is a sex-linked recessive disorder. Which shows its transmission from unaffected carrier female to some of the male progeny.
Patient continues to bleed even with a minor cut because of a defect in blood coagulation
The gene for haemophilia is located on X-chromosome.
More males suffer from haemophilia than females because in males single gene for the defect is able to express as male have only one X-chromosome.

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