Question 1. Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (use the internet).
Human insulin – Diabetes
DNase I – Treatment of cystic fibrosis.
Chronic Gonadotropin – Treatment of infertility
Human growth hormone – Dwarfism cure
Calcitonin – Treatment of rickets
TPA (tissue plasminogen activator) – Heart attack/strokes
PDGF (platelet derived growth factor) – Stimulates wound healing.
Interferon (α, β and γ) – Treatment of viral infection and cancer.
Interlinkins – Enhances activity of immune reaction,
Reo Pro – Prevention of blood clots.
Question 2. Make a chart (with diagrammatic representation) showing a restriction enzyme, the substrate DNA on which it acts, the site at which it cuts DNA and the product it produces.
Name of the Restriction enzyme – Bam HI.
The substrate DNA on which it acts –
Question 3. From what you have learnt, can you tell whether enzymes are bigger or DNA is bigger in molecular size? How did you know?
Ans: Even though both DNA and enzymes are macromolecules, DNA is bigger in molecular size as compared to proteins. Because DNA is